2014 Conference Program

2014 WAFSF on Stem Cell Research and Regenerative Medicine

Date: Thursday November 6 and Friday, November 7th, 2014
Location: Mission Bay Conference Center at UCSF, 1675 Owens Street, San Francisco, CA 94143
Organizer: Alliance Forum Foundation, USA (AFFUSA)
Tickets: General Registration: $800. For further inquiries or offers on special rates, email us at wafsf@allianceforum.org.

Thursday, November 6, 2014

08:30–9:00 Registration
 9:00–9:10 Opening & Welcome Remarks: Mr. Isao “Steve” Matsuura, Conference Co-chair and Council Member, Alliance Forum Foundation and
The Honorable Masato Watanabe, Consul General, The Consulate General of Japan in San Francisco

The Landscape of Stem Cell Research and Regenerative Medicine
Session I: Regenerative Medicine 2014

 9:10–10:50 Session Chair: Michael WernerSpeakers:

Arlene Chiu, PhD, Director of the Office of New Research Initiatives, Beckman Research Institute

“Cell Sheet Tissue Engineering for Clinical Applications,” Teruo Okano, PhD, The Japanese Society for Regenerative (JSRM) Medicine & Institute of Advanced Biomedical Engineering and Science, Tokyo Women’s Medical University

Susan L. Solomon, JD, New York Stem Cell Foundation [invited]

Yuzo Toda, Forum for Innovative Regenerative Medicine (FIRM)

Michael Werner, Alliance for Regenerative Medicine (ARM)

Jonathan Thomas, PhD, JD, Chair, Governing Board of the CIRM (Independent Citizens Oversight Committee)

10:50-11:05 Coffee Break

Session II:
Business Perspectives on the Regenerative Medicine Space

11:05–11:45 Panel Discussion:

Rahul Aras, PhD (President and Chief Executive Office, Juventas Therapeutics)

Edward Lanphier (President and CEO, Sangamo BioSciences Inc.)

Jay Lee, PhD (Senior Director, Business Development, Medipost)

Robert J. Palay, (Chairman of the Board and Chief Executive Officer, Cellular Dynamics International)

11:45–12:45 Complimentary Lunch in the Fisher Banquet Room TBA

Session III: Frontiers of Regenerative Medicine

 12:45-14:05 Session Chair: Hiromitsu NakauchiSpeakers:

“From Cells to Organs: Generation of Functional Organs from Pluripotent Stem Cells,” Hiromitsu Nakauchi, MD, PhD, Professor,Stanford University and The University of Tokyo

“Realization of iPSC-Organ Bud Transplantation Therapy,” Takanori Takebe, MD, PhD, Associate Professor, Medical Faculty, Yokohama City University

“Cell Fiber Technology for Regenerative Medicine,” Shoji Takeuchi, PhD, Professor, The Biohybrid Systems Laboratory, The University of Tokyo

From the Laboratory to Clinical Applications
A Special Presentation by Dr. Shinya Yamanaka, 2012 Nobel Laureate
[MC: Ms. Diane Dwyer, Reporter, NBC Bay Area News]

14:05-14:15 Introduction of Shinya Yamanaka: Robert Mahley, MD, PhD, Founder & President Emeritus, Professor of Pathology and Medicine, Gladstone Institutes
14:30–15:00 Keynote Speech: “Recent Progress in iPS Cell Research and Application,” Shinya Yamanaka, MD, PhD, Professor and Director of the Center for iPS Cell Research and Application (CiRA), Kyoto University; Senior Investigator, L.K. Whittier Foundation Investigator in Stem Cell Biology, Gladstone Institutes.
15:00–15:15 Coffee Break

Session IV: From the Laboratory to Clinical Applications

15:15–16:45 Session Chair: Shinya YamanakaSpeakers:

“Pre-Clinical Development of a Humanized Anti-CD47 Antibody Targeting AML Stem Cells,” Ravi Majeti, MD, PhD, Assistant Professor of Medicine (Hematology), Stanford University

“iPS Cell Technologies: Significance and Applications to CNS Regeneration and Disease Research,” Hideyuki Okano, MD, PhD,Professor, Department of Physiology, Graduate School of Medicine, Keio University; Chairman, Graduate School of Medicine, Keio University

“Induction of Immunological Tolerance by T-Regulatory Cells: From Discovery to Clinical Application,” Maria-Grazia Roncarolo, MD, Co-director, Institute for Stem Cell Biology and Regenerative Medicine; George D. Smith Professor in Stem Cell and Regenerative Medicine; Chief of the Division of Pediatric Translational and Regenerative Medicine; Professor of pediatrics and of medicine (blood and marrow transplantation), Stanford University.

Discussion: (30 mins)

Ravi Majeti (moderator), Hideyuki Okano, Maria-Grazia Roncarolo, and Shinya Yamanaka

16:45–17:05 Company Showcase
Presentation 1: TBA
Presentation 2: TBA
17:05–17:15 Closing Remarks: George Hara, Chairman, Alliance Forum Foundation
17:15–18:30 Cocktail Reception in the Main Lobby (1st Floor)

Friday, November 7, 2014

8:30–9:00 Complimentary Continental Breakfast
9:00–9:05 Welcome: George Hara, Chairman, Alliance Forum Foundation

Developments in Regenerative Medicine, 2014
Session V
Eye and Retina

09:05–10:05 Session Chair: David Hinton

“Transplantation of iPS-Derived Retinal Cells,” Masayo Takahashi, MD, PhD, Project Leader, Laboratory for Retinal Regeneration Research, RIKEN

“ES-derived RPE for the Treatment of AMD: The California Project to Cure Blindness,” David Hinton, MD, Gavin S. Herbert Professor in Retinal Research, Professor of Pathology, Neurological Surgery and Ophthalmology, Keck School of Medicine, University of Southern California

“Retinal Progenitor Cells for Treatment of Retinitis Pigmentosa,” Henry Klassen, MD, PhD,Associate Professor and Director, Stem Cell & Retinal Regeneration Program, Ophthalmology, School of Medicine, University of California, Irvine

“Human Neural Stem Cells: Potential Application for Dry Age-Related Macular Degeneration,” Ann Tsukamoto, PhD, Executive Vice President, Scientific and Strategic Alliances, StemCells, Inc.
10:05–10:35 Company Showcase Presentation 3: TBA
Presentation 4: TBA
Presentation 5: TBA
10:35–10:50 Coffee Break

Session VI

10:50-11:50 Session Chair: Deepak Srivastava

“Regenerative Therapy for Severe Heart Failure Patients,” Yoshiki Sawa, MD, PhD, Division of Medicine Graduate School of Medicine, Osaka University

“Cardiac Reprogramming for Regenerative Medicine,” Deepak Srivastava, MD, Director and Senior Investigator, Gladstone Institute of Cardiovascular Disease; Director, Roddenberry Center for Stem Cell Biology and Medicine; Professor, Departments of Pediatrics and Biochemistry & Biophysics, University of California, San Francisco; Wilma and Adeline Pirag Distinguished Professor in Pediatric Developmental Cardiology, University of California, San Francisco
“Cardiac iPSCs for Disease Modeling and Drug Discovery,” Joseph C. Wu, MD, PhD, Director, Stanford Cardiovascular Institute, Professor, Dept of Medicine/Cardiology & Radiology, Stanford University School of Medicine
11:50–12:20 Company Showcase Presentation 6: TBA
Presentation 7: TBA
Presentation 8: TBA
12:20–13:20 Complimentary Lunch in Fisher Banquet Room TBA

A Promise of Life Science Revolution

13:20–13:30 Introduction of Mahendra Rao
Ken-ichi Arai, MD, PhD, Professor Emeritus and former Director of the Institute of Medical Science, The University of Tokyo (IMSUT) (tentative)
13:30­–14:00 Keynote Speech on “Moving iPSC to the Clinic–Issues and Solutions,” Mahendra Rao, MD PhD, Vice-president of Regenerative Medicine, New York Stem Cell Foundation and former Director, NIH Center for Regenerative Medicine
14:00–14:40 Conversation: “Conversations on Stem Cell Research on the Potential of Mesenchymal Stem Cells (MSC) for Clinical Use; and Rethinking Translational Research.”Ken’ichi Arai, MD, PhD, Professor Emeritus and former Director of the Institute of Medical Science, The University of Tokyo (IMSUT), Shigetaka Asano, MD, PhD, Professor Emeritus, School of Science and Engineering, Waseda University, The Institute of Medical Science, The Tokyo University (IMSUT) [tentative]
14:40–15:10 Company Showcase Presentation 9: TBA
Presentation 10: TBA
Presentation 11: TBA
15:10–15:25 Coffee Break

Session VII
The Future of Regenerative Medicine: Five, Ten Years from Now

15:25–15:55 Speech on “The Future of Regenerative Medicine” (tentative)
Regis Kelly, PhD, Director, QB3, University of California, San Francisco
15:55–16:35 Panel Discussion moderated by Regis Kelly

Thea Tlsty, PhD, Director of the Center for Translational Research in the Molecular Genetics of Cancer, University of California, San Francisco

David Schaffer, PhD, Director of Stem Cell Center, University of California, Berkeley

Allan Basbaum, PhD, Professor and Chair, Department of Anatomy, UCSF School of Medicine [tentative]

16:35–16:50 Concluding Remarks: Mr. George Hara, Chairman, Alliance Forum Foundation
16:50–18:00 Cocktail Reception


Please visit this link to learn about business opportunities available at this year’s Conference.

Stem cell research is quickly developing today, as are the possibilities of its applications, which range from disease research and drug development to experimental growth of entirely new organs. Stem-cell technologies harbor the potential for a paradigm shift in regenerative medicine, healthcare, and society at large. However, many challenges still need to be overcome before we will be able to reap the benefits.

  • discuss the exciting possibilities of stem-cell applications and how they will affect our future;
  • examine the accompanying research and business and regulatory hurdles;
  • facilitate the establishment of networks of researchers, entrepreneurs, large corporations, policy-makers, and patient advocates for the development of regenerative medicine as a sustainable industry; and
  • encourage the building of a new business environment where “public interest”  becomes the guiding standard and where successful businesses reallocate a portion of  their profit to basic research, as well as to other stakeholders in the new ecosystem.

The Conference will be lead by internationally recognized figures working primarily in the Bay Area and Japan. The Conference will also bring together venture capital and businesses already involved in, or expected to play a significant role in, the future development of regenerative medicine as a new health delivery system. We also look forward to the participation of regulators, rare disease philanthropists, and patient advocates so that a diverse range of stakeholders will be represented.

With its sessions, pre-session workshops, and business presentations, the Conference will provide the best opportunity to meet with people from the Bay Area and Japan, share views and knowledge, build new relationships, and explore business opportunities!